Health

COVID: Insights Gained, Lessons Unheeded

In January 2021 I wrote the first in what became a series of articles in Quadrant on the immunology and treatment of COVID-19. My objective was to give a balanced, science-based understanding of the immunopathology, for those without medical training, of COVID-19 and a critique of treatment options. As a clinical immunologist with 50 years of research into the relationship between infection of the airway and the immune response to it, I felt well placed to contribute to the discussion. My home University had recently awarded me a Doctor of Science and I was informed this was the first such award by that university.

At a time when COVID-19 was more severe, with 20 per cent admitted to hospital and a mortality in excess of 1 per cent, the mantra was “stay at home until you have a significant problem breathing”. This was despite the availability of highly effective, safe repurposed drugs but not approved for COVID even though these medications reduced hospitalisation and mortality by 80 per cent! I flagged concerns in the article regarding efficacy and safety of novel untested genetic “vaccines”. Concerns were based on the principles of mucosal immunology, the systemic distribution of the spike protein (the antigen coded for by the mRNA) that presented a potential for “autoimmune” damage, as well as the emerging idea that the spike protein itself was toxic.

This article will review progress in understanding over the last two years, with comment on success of vaccine roll-out and intervention therapy.

THE PANDEMIC

First, a question: How has the COVID-19 pandemic evolved in Australia over the last three years in relation to world experience?

Through 2020 there were few COVID cases in Australia, about 10-20 new cases a day except for a peak in August-September of up to 1500 infections per day. The mortality rate for most of that year was around 1 per cent, except during the August peak, when it rose to around 5 per cent. This pattern continued through to late 2021.  Coincident with the ending of community lockdowns, the appearance of the new and highly infectious variant, Omicron (but with lower pathogenicity compared to earlier variants), and the onset of the vaccine booster programme, a significant change in pandemic dynamics occurred. Some 80 per cent of all COVID deaths in Australia were recorded over the next 10 months. Reduction in testing and mildness of disease led to gross underestimates of the incidence of infections – making mortality data a more reliable indicator of COVID infection rates, which could be estimated at upwards of 10,000 cases per day during disease peaks in January and August of 2022. Testing blood for antibodies to nucleocapsid antigens, present only in the intact virus, showed that 85-95 per cent of the Australian population had been infected. Forty percent of children with no clinical history of infection have anti-nucleocapsid antibody, reflecting past asymptomatic COVID-19 infection. By mid-February 2023, diagnosed infections had fallen to about 2,500 per day with 35 recorded deaths daily.

How does this compare with the world experience?

Using mortality rates again as an indicator of disease impact, in 2020, when very few deaths were recorded in Australia, the world daily death rates was about 0.8 per million population, increasing through 2021 to approximately 1.5 per million. This differed from Australia, with few deaths, until late 2021. However for the 12 months from November 2021, the average death rate rose to approximately 1.6 per million population, twice that of the average world mortality. From the period of May to December 2022, when daily deaths from COVID-19 in Australia were about 1.5 per million, the world rate had fallen to 0.3 per million.

These statistics indicate that over the course of the pandemic the total number of deaths per million of population in Australia and the world was similar. Was this because geographic and “lockout” isolation effectively reduced early infection rates, with consequent reduction in acquisition of natural immunity (which gives more effective protection than do vaccines)? The high “catch-up” COVID mortality rates in Australia during 2022 may reflect an infectious variant in an immune naive population due to lockdowns. But how could that be as by February 2022 half the population was triple vaccinated? Official NSW figures for COVID-19 in November 2022 showed essentially all hospitalised patients had multiple vaccinations. Together these data question the value of multiple vaccinations through 2022. Experience in the elderly asks a similar question: 80 per cent of the 4,000 pandemic deaths in aged care were in the first nine months of 2022, with a mortality rate of 3.5 per cent. Yet Christopher Knaus of The Guardian (24/9/2022) stated “there was cause for recent optimism—as vaccines are working [and] 84.5% of eligible residents have received their fourth dose”.

To summarise, the course of COVID-19 in the world over three years followed the pattern of influenza pandemics, with significant mortality replaced by highly infectious but less pathogenic variants. For perspective, the total COVID-19 deaths at 6.7 million was about 10 per cent of the 1918 influenza pandemic, and only 50 per cent more than the most recent influenza pandemic in 1968. The Wuhan isolate gave way to the Delta variant which dominated through 2021. Delta was more infectious than the Wuhan variant, while retaining significant pathogenicity. Then came a genetic jump to the Omicron series with significant antigenic drift (point mutations) and, in some variants, shift (where large chunks of genetic material change due to recombination events occurring in host cells infected with more than one variant virus). Omicron variants dominated from early 2022. The significant mutations in the Omicron series led to “antigen escape” from antibodies stimulated by early vaccines. By the time mRNA vaccines were produced to include sequences that covered early Omicron subvariants BA.4 and BA.5, major shifts in antigen were such that sub-variants currently circulating such as XBB 1.5 , (75 per cent of infections) and BQ 1.1 (15 per cent of infections) largely escape vaccine-induced protection and are unaffected by monoclonal antibody therapy that had been developed to protect against earlier variants.

Summary: In Australia few infections and deaths occurred in the first two years, when the original Wuhan strain and then the Delta variant were the dominant pathogens. From the end of 2021 “catch-up” COVID occurred when the less pathogenic Omicron variant dominated, with tens of thousands of cases and upwards of a hundred or so deaths each day, as society and international travel opened. The ballooning of COVID deaths in a highly vaccinated population through mid and late 2022 questions the efficacy of the vaccination strategy.

Returning to the topics covered two years ago, surprisingly little has changed, although, much detail has been added.

 

1/ Pathogenesis of COVID-19 AND Long COVID

COVID-19 is an infection of the airway and thus subject to the rules of mucosal immunity. A set of mutations enabled a corona virus to escape the mucosal compartment, to enter the gas exchange apparatus of the lungs, thus entering the domain of systemic immunity characterised by IgG antibody. Disease or protection outcomes of infection depend on the balance between antigen (the virus) and antibody: “antigen excess” promotes disease while “antibody excess” promotes protection. The significant difference between mucosal and systemic immunity, is a dominant suppression mediated by T reg cells distributed to mucosal and systemic sites. Models explaining the power of suppression include allergy shots to “turn off” allergic inflammation, and “oral immune tolerance” in mucosal and systemic tissues to explain immune non-responsiveness to food antigens. Inhaled viruses have short term immunity and cause repeated infections. Invariably, these vaccines perform poorly compared to vaccines against systemic infections such as measles.

One surprise discovery in regard to COVID was damage of cell function by spike protein due to a toxic effect on energy production and abnormal folding to form amyloid tissue (the pathology of prion disease and Alzheimer Disease), especially within neural tissue. Damage to the endothelium lining blood vessels and agglutination of red cells causes clots and oxygen desaturation.

Long COVID, an outcome of COVID-19 infection, occurs in about 10 per cent of cases. Risk factors that include more invasive variants, severe disease and subtle immune deficiency suggest persistent virus as a key pathogenic factor.  Initially structural damage following acute infection confused diagnosis, which remains one of exclusion. Core symptoms are fatigue made worse with activity and cognitive impairment commonly described as “brain fog”. Identical symptoms can follow COVID-19 vaccination. Observations that both mRNA coding for spike protein and the spike protein itself can persist in tissues for months, connect persistent infection and vaccine-antigen as putative drivers of a chronic fatigue syndrome due to defective immune clearance. How does that fit?

Study of a model of impaired performance in elite athletes, representing the “tip of the fatigue iceberg”, may be a model for Long COVID.

Studies in elite swimmers at the Australian Institute of Sport produced interesting results.  First, “fatigue” (or impaired performance) was predicted by subtle defects in mucosal immunity which, in turn, related to their training schedules. Second, impaired  performance in those with immune suppression correlated with excretion of EBV (the virus causing Glandular Fever, which becomes integrated in host DNA, and contained by strong immunity). Third, impaired performance was prevented by changing the training schedule or by anti-viral therapy.

Several disconnected observations “fit” with the idea that persistent COVID-19 virus (or spike protein) and immune dysregulation may underpin Long COVID: the clinical risk factors; T reg-mediated immune suppression; persistent antigen; inflammation markers; appearance of dysregulation indices including IgG4 (an anti-inflammatory antibody) and check point inhibitors such as PD-1 and its ligands (that control T cell activity).

A testable hypothesis for Long COVID is “that persistent spike protein (as intact virus or post mRNA vaccine) due in part to an imperfect immune clearance, drives persistent inflammation with core symptoms of fatigue and impaired cognition”. Studies to test this hypothesis could include high dose ivermectin, or metformin — drugs causing accelerated viral clearance and, in the case of metformin, reduced incidence of Long COVID. Ivermectin blocks spike protein clumping of red cells and could be tested as a candidate to neutralise spike protein toxicity.

 

2/ Genetic vaccines

These were introduced by January 2021, with claims of 90 per cent protection against clinical infection. These were followed by observational studies claiming significant protection against severe disease, especially in the elderly.

However, concerns were raised regarding claimed efficacy and safety.

Blunted enthusiasm for efficacy was based on lessons learnt from 80 years of experience with vaccines for influenza. Both COVID-19 and influenza vaccines simulate IgG antibody which protects the lungs’ gas-exchange apparatus against severe disease. Injected vaccines have little effect on the mucosal phase of infection and thus on viral transmission. And protective responses were limited by immune suppression that dominates following boosters. High mutation rate in influenza RNA requires constant adjustment of vaccine formulation to cover contemporary antigens. In COVID-19 management neither vaccination nor monoclonal antibodies have kept up with antigen variations, noticeably recent subvariants such as XBB 1.5. Major genetic change is due to recombination of large chunks of genetic material between two viruses infecting the same cell. A similar trend occurred with natural antibody decline of protection. Less efficient vaccines risk selection of resistant COVID-19 variants with unpredictable outcomes.

The examples discussed above of allergy shots and oral tolerance predict similar downregulation following poorly considered vaccine strategy. Booster injections provide a temporary increase in protection of 30-40 per cent but are followed in a couple of months by “negative immunity” with more frequent and more severe infections. The change in COVID dynamics in Australia at the end of 2021 was a perfect storm of reduced community lockdowns, a new viral variant not well covered by existing vaccines, and the introduction of the vaccine-booster rollout. By November of 2022, patients admitted in NSW hospitals were nearly all triple vaccinated. mRNA vaccines appear more prone to immune suppression as there is no control over the amount, the site or duration of antigen production. Persistent antigen and mRNA following vaccination are documented. Immunity is a finely balanced response, which includes antigen excess downregulating antibody production.

Safety must always be the predominant consideration associated with vaccine administration: “First do no Harm”. Red flags have been raised around the world with the rollout of genetic vaccines on a “trust-me” basis. 96% of Australians have had at least two doses, with 72 per cent having a booster and facing a fourth or fifth dose. Nearly two million children have two doses of vaccine.

The question never answered is why there is need for an unprecedented 4 to 5 vaccinations over just two years when airway infections have never responded well to vaccines? COVID antigen variation constantly outstrips vaccine adaptation and response is dominated by downregulation that increases following multiple injections. The severe adverse event profile associated with mRNA vaccines includes anaphylaxis, systemic tissue damage due to toxic spike protein and/or immune response to spike protein expressed on cells throughout the body (much as in autoimmune disease) and longer term and transgenerational outcomes due to transcription of coded information into host DNA.

Anaphylaxis (a life-threatening allergic reaction) occurs with 11 of 1,000,000 injections. It is common to many vaccines and usually easily treated. Further vaccinations are then proscribed. Implications of documented reverse transcription of genetic information from COVID-19 vaccines are unknown; resolution of potential threats is a priority concern. The following discussion focusses on the portfolio of serious adverse events, including death, that are being reported.

Misinformation about adverse events is not new. Claims of fraudulent handling of data from the original Pfizer trials (“The many inconsistencies in the Pfizer approval study”) were surprising only because they were published in “Die Welt” the national German paper. The international mainstream press (under the Trusted News Initiative) resisted reporting data that interferes with the vaccine narrative. Serious adverse events following vaccination are reported in national data bases such as VAERS in the US. Reports of death linked to COVID-19 vaccines is 40 times that of reports for all other vaccines, combined, since 1990 (with underreporting recognised to be 10 to 40-fold).

Argument supporting widespread vaccine-related deaths comes from population studies. Prominent has been recognition of an excess in mortality linked to vaccination programmes in most countries, including Australia. An unexpected and unprecedented spiked increase of 400 per cent in India during a four-month period in 2021 correlated with the vaccine rollout. This contrasted with zero increase in reported deaths during the previous 12 months of the pandemic. There could be other causes. Professor Norman Fenton (London) considered all feasible causes of increased mortality. He analysed world excess mortality data through 2022. He was able to exclude COVID-19 infection, Long COVID, impact of lockdowns and quality of healthcare as potential causes. Between week 12 and 24 of 2022 there was a significant linear correlation with vaccine rollout. Fenton concluded there was a strong signal that vaccine programmes caused a proportion of the excess deaths and that subjects in the higher socio-economic category were most impacted.

Using another approach, Dr Wilson Sy analysed Australian data, using criteria first used by Bradford Hill, to support causality. He concluded that increased mortality correlated with the vaccine programme starting five months previously. Analysis of Medicare data in the US on deaths among those under 80 in 2021, showed markedly different curves over time from vaccination, between influenza and pneumococcal vaccination, and COVID-19. For both influenza and pneumococcal vaccines deaths at around 50 were stable, as expected, if the vaccines did not impact mortality. COVID-19 vaccination was followed by a ten-fold increase in mortality, returning only slowly to the baseline. Closer to home are data from the New Zealand government. Through 2022 to January 2023 for every age group, COVID-19 infection was more frequent and resulted in a higher risk of dying the higher the number of vaccinations.

Post-mortem studies have identified spike protein on the surface of damaged cells, surrounded by an infiltrate of T cells, especially in the heart and brain. In German subjects dying unexpectedly, post-mortem studies found 15 per cent were due to post-vaccine damage. The value of prospective studies was shown in Thai schoolboys, with 2 per cent to 3 per cent having laboratory evidence of cardiac damage following mRNA COVID vaccination. This is in contrast with hospital data recording clinical myocarditis at one in 5,000 to 10,000. Scars from subclinical lesions may initiate ventricular fibrillation if exposed to a surge in adrenaline, perhaps explaining the increased incidence of death of athletes. The link to sub-clinical myocarditis is consistent with recent post-mortem diagnoses of “catecholamine-mediated stress cardiomyopathy”, following vaccination.

 

EARLY TREATMENT

A serious concern, going to the heart of the doctor-patient relationship and the value of “off-label” treatment, has been the cancellation of safe, effective (and inexpensive) therapy that would have saved Australian lives. With TGA approval, following dubious studies, of molnupiravir and remdesivir, anti-viral agents costing thousands of dollars per course with minimal effect and significant toxicity concerns, doctors assumed drug therapy was no longer a threat to vaccine rollout. This was the first reason given to explain earlier cancellation of ivermectin. Trials of ivermectin trials now number 95 involving 134,500 subjects with over 1,000 authors. What they show is a 62 per cent improvement (P<0.0001) including 45 randomised controlled trials. However, in a provisional announcement the goal posts were moved: “More data is required” said the TGA! To repeat (with a weary shake of the head), “More data is required”!

Ivermectin has dramatically changed COVID-19 outcomes in numerous regions and countries across the world, including Utah Pradesh (India) and areas of South America. The recent demonstration of dramatic reversal of oxygen desaturation following ivermectin use, due to inhibition of red cell clumping as a mechanism of action, brings together an immense supporting data base. The targeted attack on ivermectin at every level is without precedent or logic.

Compared to the two antiviral drugs, Ivermectin has a broader treatment window. It is the only one of the three drugs effective in prophylaxis (82 per cent effective in 20,000 subjects), and the only one without restrictions due to age or medications.

 

CONCLUSION

COVID-19 has become endemic and a milder disease but remains highly transmissible. Awareness of the limitations of genetic vaccines is apparent, although resistance by authorities to change continues. COVID-19 and influenza vaccines share limitations common to all airway virus infections: limited efficacy, inability to prevent mucosal infection or viral transmission. They do not induce sterilising or herd immunity. Cumulative deaths from COVID-19 in Australia align with world figures. The shift in Australian mortality in 2022 in a highly vaccinated population questioned both vaccination efficacy against new variant virus and the capacity of industry to match antigen change with effective genetic vaccines. Programmes based on repeated vaccination without considered spacing, to avoid net suppression and disease promotion, reflect the dominance of narrative over scientific knowledge. The extraordinary act of registering two relatively ineffective and untested antivirals with many disadvantages, costing over $A1,000 per course, while refusing to accept cheap, effective repurposed drugs, reflects a new reality for medicine in the COVID era where clinical decisions are made outside the traditional doctor-patient relationship.

There are numerous reasons why mRNA vaccines – be they the current COVID-19 vaccines or planned vaccines to be produced from new manufacturing plants in Australia (all new mRNA vaccines will share the potential dangers of systemic antigen synthesis and incorporation of genetic information into host DNA) – should be stopped, investigated, and modified if found wanting, to comply with traditional regulatory standards. There is no evidence that genetic vaccines offer advantage over antigen vaccines.

The two-year Report Card is a simple one: a lot of red flags to be heeded and one green one to be acted upon!

14 thoughts on “COVID: Insights Gained, Lessons Unheeded

  • Phillip says:

    Now here is a statement;
    The same gullible people who took the covid jab poison are the same type of people who blindly support funding Ukraine and the corrupt Zelensky.

    The media dupes people into believing a narrative to market for an outcome before they (the people) conduct their own personal research for truth.

    The fact that Police were arresting mothers in dressing gowns for posting innocent facebook messages and Doctors were being de-registered for not advocating the pfizer poison, are simple flags to indicate that something smells here.

    The whole covid scam was/is one of the most deplorable acts committed by evil governments to control people by fear. The so called ‘vaccine’ has nothing to do with science or medicine to cure. It was created for an outcome to kill and mame.

    • john mac says:

      Philip – you could add the same gullible drones who believe the climate scam hook ,line and sinker . Ukraine is a convenient “look over there” issue for our craven Western “Leaders” and frankly I’m more concerned with the collective malfeasance of them than the likes of two Vodka swilling nations , one of which is led By a b grade comic , the other a predictable villain and scapegoat , who at least stands alone in his patriotism ( a dirty word to our betters) . IMacs response itself predictable , and he “Whatever his name is” , lemming like will march off the cliff , vaxxed , masked and self-righteous to the end .

  • Ian MacDougall says:

    “The whole covid scam was/is one of the most deplorable acts committed by evil governments to control people by fear. The so called ‘vaccine’ has nothing to do with science or medicine to cure. It was created for an outcome to kill and mame. (SIC!)”
    And ‘Phillip’ or whatever his real name is, manages to combine this little bottler of a conspiracy theory with an endorsement of Vlad Dracula, I mean Vlad Putin.
    Ever since Archimedes, all branches of science have rested on empiricism: on facts as best we can discover them. All other approaches have been tried and found wanting. While some went up blind alleys, like the phlogistonists re combustion, other players were far more cynical and greedy. Read Witches, Midwives, and Nurses: A History of Women Healers by Barbara Ehrenreich and Deirdre English for another slant on the history of Western Medicine. (Find it at https://www.feministes-radicales.org/wp-content/uploads/2012/06/Barbara-Ehrenreich-and-Deirdre-English-Witches-Midwives-and-Nurses-A-History-of-Women-Healers.-Introduction..pdf )
    Things have moved on a bit since the Black Death 1347 – 1351, which took out 3/4 of the population of Europe. Covid denialists and antivaxxers could well be doing their well-meaning best to soften us all up for the Next Big One, which in turn could well put Covid into the Sunday School Picnic class.

    • Bruce Bailey says:

      Ian, The time when “Science” depended on empiricism is past if indeed it ever existed. Phillip has used his powers of observation well.
      Covid 19 was a Psyop and had little to do with the ideal of empirical science.
      People who once believed they lived in free societies lost those freedoms, mostly compliantly.
      Those who should have protected our freedoms and health not only failed but profited from the lies.
      The mantra “safe and effective” was only one of many lies.
      The real question is why? We already know who did it.
      My question is; was it mere incompetence? or was it deliberate?
      In either case I would like to see some accountability sooner rather than later.
      I for one have lost faith in so much I once admired including the Medical Profession and the character of my fellow countrymen.

      • Phillip says:

        Bruce Bailey has given the correct explanation to my post.
        My frustration with the hypocrisy and what we have all experienced for the last few years is very well explained by Dr Clancy.

      • Jackson says:

        Well said, Bruce Bailey.
        I share your loss of faith in the medical profession and fellow countrymen. It is worth enumerating some particularly egregious examples of the latter, in the interests of their accountability:
        – The MainStreamMedia (but, then again, my erstwhile “faith” in them was naively and grievously misplaced. TheOz comes in for special mention and infamy, as I had thought they were the last bastion of common-sense and “reasonably” objective journalistic/editorial standards. I should have, and now do know better).
        – Our political “leaders” (more accurately, poll-followers, crowd-pleasers and craven clingers to power at all costs, motivated by the (sometimes, no doubt sincere) desire to act for the “greatest good of the greatest number”). One has come to expect politicians of the Left to go with their collectivist instincts and act as they did (but even then, it was gob-smacking to see how far wrong and badly things went in VIC), but for the Liberal government in NSW to cave as they did from July2021 was the final nail in the coffin for my “faith” in them. And they still have the temerity and brazenness to maintain that they did a good job “keeping people safe”.
        – The civil rights lawyers and activists, who are normally so quick out of the blocks when any right-of-centre government or organisation putatively violates an individual’s “human rights”. This lot were completely MIA when it came to defending the rights of individuals against violations of the principles of informed consent, freedom of speech and association, freedom of information and accountability of the Executive to Parliament, and against governmental coercion and propaganda.
        – The Courts, who refused to hear or who threw out cases brought against the above violations.
        .
        Most discouragingly, it appears that most people are still compliantly complacent about having given up the freedoms of our hitherto free society, not even being aware of the loss, much less lameting, protesting or litigating it. Stockholm Syndrome writ large, and ongoing. Thus, many thanks to those who are prepared to wear the ongoing social opprobrium attaching to calling all of this out – Prof Robert Clancy, Quadrant Magazine, and so many other individuals and organisations. May all of these efforts succeed in the fullness of time.
        .
        Here endeth the Tirade.

    • Citizen Kane says:

      ‘Covid denialists and antivaxxers could well be doing their well-meaning best to soften us all up for the Next Big One, which in turn could well put Covid into the Sunday School Picnic class.’ – sounds like a dyed in the wool conspiracy theory to me.

      Of course, Emeritus Professor Clancy must be an ‘antivaxxer’ to query the safety and efficacy of mRNA agents, which co-opt your own cells protein synthesis to make a foreign protein (in this case the Covid-19 spike protein) in contrast to the classical antibody mediated immunization elicited by the introduction of an attenuated and or modified antigen (which is very time limited in its circulation) as provided by all other types of vaccines. Furthermore, the numbers simply don’t lie. NSW was the only Australian jurisdiction to keep and publish consistent data, which clearly demonstrates (as early as December 2021) the high level of vaccinated patients that required serious medical intervention and or died outstripping (pro rata) those who were unvaccinated, except in the very old (85+) who were often unvaccinated because it was contraindicated against other serious co-morbidities. Add to this, that there is no credible evidence whatsoever that mRNA vaccination prevented infection and/or transmission and the overall case is damning.

      But I guess the cow farmer knows best!

  • Peter Marriott says:

    Thank you Dr. Clancy for putting this together for us, it’s obviously taken quite some thinking and time. On the death figures I’m still of the view that most die with this virus, not of it, as of course could be said of other viruses, but by not acknowledging this much fear has spread.
    A good example I think could be a morbidity such as Chronic Obstructive Pulmonary Disease, which would make it quite dangerous for the sufferer to catch anything, even a common cold however in the event of succumbing this would most probably be recording as due to the COPD, not the cold….which does not seem to have been the case with this covid virus, which seems to have been recorded the other way around.
    With the TGA I find it incredible that with all the reported recorded testing of Ivermectin they can airily wave it away and state more data required. Surely they must state just what data is required otherwise it smacks of pure cover up….surely ?

    • tommbell says:

      Sadly the fix has been in for sometime. No change in sight. And as the evidence gets more damning new walls are erected to obscure vision of the truth.

  • ianl says:

    A complete tell: the resident trollster, McDougall, rants away with his usual silly low level sarcasm and completely avoids any engagement with the actual highly literate and precise article from Dr. Clancy.

    I value hard information. Robert Clancy has provided it.

    • gareththomassport says:

      Agree entirely.
      Whilst reading McDougall’s reply, I was left wondering where the responses were to Prof Clancy’s article.
      The use of the performative “anti-vaxxer” sets the tone.
      My reading of empirical and scientific data with a background of 40 years in medicine aligns largely with Clancy’s views.
      When one further examines possible underlying motivations of the media, public service and politicians in perpetuating the catastrophe that has been the Covid response, one can only settle on malign intent or abject stupidity.

  • jjprineas says:

    Dr Robert Clancy has worked 50 years in the Science of Medicine (immunology) and now proposes testable hypotheses for the causes and effects of ”Long Covid”” disease Meanwhile , Dr John Campbell a medical educator who entered the healing Art from the Nursing perspective some forty years ago is apologizing publicly for having misled his You-tube audience regarding the efficacy of face masks. which everybody now knows that they have none. These two Doctors have been the most ethical, realistic and fearless influences on You-tube and their Covid discussions have been the most educational on the Net.
    Yet one is apologizing publicly for misleading his audience throughout the Covid ”Emergency” while the other is still chasing rainbows. Everybody can be wrong on some things and make mistakes on others
    . It is the duty of the GP to ensure that the cobbler keeps to his last but a look around sees that what has become of General Medical Practice is not fit for purpose. Artificial Intelligence has overwhelmed the Art of medicine
    This Surburban GP is now retired and free to scribble whatever on covid or doctors. An essay on Covid and Doctors submitted to Quadrant appeared in the October 2022 Quadrant but it then disappeared into the archives without exposure or comment on line. For the sake of enlightenment and sanity, keep the comments coming into Dr Clancy’s essay in the last free and intelligent venue left in the country.

  • vickisanderson says:

    Professor Clancy has once again provided an informed, eloquent and restrained analysis of the fiasco of the imposition of the genetic “vaccines” on our population.

    The overwhelming global evidence of excess mortality over the last year or so must surely disrupt the hypnotic belief in these medical interventions. I am convinced that doctors and other medical staff have clearly come to recognise that the confidence in the mRNA treatments is misplaced. But concern for jobs and careers have stymied all dissent.

    There has been good evidence for the efficacy of a number of early treatments but this latest study of the ability of Ivermectin to dramatically reverse oxygen desaturation should be a game changer. It is a scandal of monumental proportions that lives have been sacrificed needlessly over the past three years.

  • pmprociv says:

    With all due respect to Prof Clancy, I must stress that even senior scientists and doctors are only human beings, not always infallible, and even prone to subjectivity like everyone else. And Quadrant certainly doesn’t claim to be a peer-reviewed, authoritative medical journal! While much of what the good professor writes here about immunology sounds impressive, I know that it’s an extremely complex and confusing field about which we still have much to learn, and in which there’s still considerable disagreement and controversy. As someone with a strong professional interest in ivermectin over many years, I have frankly been baffled by all the propaganda extolling its virtues for treating COVID, and there’s no denying that some of the supportive studies have been fraudulent. While the medical profession can succumb to orthodox thinking (for good reason), I don’t buy that a massive conspiracy could be sustained for long within its ranks. (What politicians get up to is another matter . . . )

    For anyone interested, here’s a summary of a reliable, recent study of ivermectin’s status as a therapeutic agent for COVID: https://www.skepticalraptor.com/skepticalraptorblog.php/higher-doses-of-ivermectin-still-useless-against-covid-19/?fbclid=IwAR1A64Zf0POUjXueRcCUidAujMrr-3kY0A8FRzPLqUCYWQOAL1o64e7dspw

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